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Mfg Part Number

Ab04698-10.3

Vector Labs Ab04698-10.3 Anti-Cystatin C [LC01], Human IgG1, Fc Silent™, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing BALB/c mice with recombinant human cystatin C protein.

$570.70

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Description

Product Class: Purified
Clone ID: LC01
Heavy Chain Modification: Fc Silent™
Synonyms: CysC; Cys C; CST3; Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin; cysteine protease inhibitor C
Amount: 100 μg
Application Codes Clone: ELISA
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG2b
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds human cystatin C. This protein acts as an inhibitor of cysteine proteinases found in a variety of biological human fluids and secretions and acts as a regulator for its enzymatic activity. A mutation in the gene expressing cystatin C has been associated with amyloid angiopathy. This protein is secreted by all nucleated cells and is freely filtered by the glomerulus. Therefore, serum concentration of cystatin C has shown great clinical potential as a biomarker of acute kidney injury or to access renal function. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role as a marker in vascular disease evaluation.
Application Notes: The binding reactivity of this antibody for human cystatin C was determined using ELISA. This antibody can be used for the analysis of cystatin C presence in serum samples using latex turbidimetry (CN116535513).

Product Class:	Purified
Clone ID:	LC01
Heavy Chain Modification:	Fc Silent™
Synonyms:	CysC; Cys C; CST3; Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin; cysteine protease inhibitor C
Amount:	100 μg
Application Codes Clone:	ELISA
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG2b
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody binds human cystatin C. This protein acts as an inhibitor of cysteine proteinases found in a variety of biological human fluids and secretions and acts as a regulator for its enzymatic activity. A mutation in the gene expressing cystatin C has been associated with amyloid angiopathy. This protein is secreted by all nucleated cells and is freely filtered by the glomerulus. Therefore, serum concentration of cystatin C has shown great clinical potential as a biomarker of acute kidney injury or to access renal function. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role as a marker in vascular disease evaluation.
Application Notes:	The binding reactivity of this antibody for human cystatin C was determined using ELISA. This antibody can be used for the analysis of cystatin C presence in serum samples using latex turbidimetry (CN116535513).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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