Mfg Part Number
Ab04711-23.0
Vector Labs Ab04711-23.0 Anti-MPXV A29L protein [4E9], Rabbit IgG, lambda (100 μg)
Quick Overview
The original antibody was generated by immunizing transgenic mice having human antibody genes with purified monkeypox virus A29L protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 4E9 |
| Synonyms: | Mpox; MPXV; Monkeypox virus; Monkey pox virus; MONPV; IMV surface protein; IMV protein; surface envelope protein |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds the A29L protein of the monkeypox virus. Mpox is an infectious disease caused by the monkeypox virus which can be transmitted to humans through physical contact with someone who is infectious, with contaminated materials, or with infected animals. It can cause a painful rash or mucosal lesions which can last 2–4 weeks, enlarged lymph nodes and fever. Monkeypox mortality rates range from 0%-11% in the general population and are higher in young children. In Q3 of 2024, the WHO declared monkeypox a Public Health Emergency of International Concern. This product serves as a powerful tool for related research efforts. |
| Application Notes: | The original mouse IgG antibody binds monkeypox virus A29L protein with a binding affinity in the sub-nanomolar range. This antibody can be used as a capture or coating antibody in a double antibody sandwich ELISA in combination with 7B10 as a labeling or detection antibody. The sensitivity of detection for this antibody pair is reported to be 0.5ng/ml (CN116284349). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |