Mfg Part Number
Ab04715-15.0
Vector Labs Ab04715-15.0 Anti-MPXV M1R protein [mab26], Human IgM, lambda (50 μg)
Quick Overview
The original antibody was generated by immunizing mice with purified monkeypox virus A29L protein.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | mab26 |
| Synonyms: | Mpox; MPXV; Monkeypox virus; Monkey pox virus; MONPV; IMV membrane protein; M1R; MPXV-COP-074; MPXV-SL-074; MPXV-WRAIR074; MPXVgp080; Myristylprotein |
| Amount: | 50 μg |
| Application Codes Clone: | neutralize; therapeutic |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds the M1R protein of the monkeypox virus. Mpox is an infectious disease caused by the monkeypox virus which can be transmitted to humans through physical contact with someone who is infectious, with contaminated materials, or with infected animals. It can cause a painful rash or mucosal lesions which can last 2–4 weeks, enlarged lymph nodes and fever. Monkeypox mortality rates range from 0%-11% in the general population and are higher in young children. In Q3 of 2024, the WHO declared monkeypox a Public Health Emergency of International Concern. This product serves as a powerful tool for related research efforts. |
| Application Notes: | This antibody was used in the development of LNP-encapsulated mRNA molecule (mRNA-mab283-LNP) which provided protein when tested in vivo in mice infected with vaccinia virus (VACV) (PMID: 38531869). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |