Mfg Part Number
Ab04716-23.0
Vector Labs Ab04716-23.0 Anti-PspA [2B11], Rabbit IgG, lambda (100 μg)
Quick Overview
The original antibody was selected from a synthetic human scFv library through biopanning against recombinant PspA.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 2B11 |
| Synonyms: | Pneumococcal surface protein A |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; BLI; IB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the Streptococcus pneumoniae PspA. The epitope on PspA was defined to residues 231-242 by mutational analysis and supported by molecular docking analysis. |
| Application Notes: | The dissociation constant (Kd) of the original human scFv version of this antibody was 5.3 ± 2.3 nM as measured in a biolayer interferometry assay. This antibody detected PspA in immunoblots; it exhibited a dose-dependent recognition of recombinant PspA with no cross-reactivity towards other tested pneumococcal antigens and also detected endogenous PspA from pneumococcal lysates (Jang et al., 2017; PMID: 27845043). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |