Mfg Part Number
Ab04730-10.3
Vector Labs Ab04730-10.3 Anti-Human Chorionic Gonadotropin [AB2], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
Vector Labs Ab04730-10.3 Anti-Human Chorionic Gonadotropin [AB2], Human IgG1, Fc Silent™, kappa (100 μg)
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | AB2 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | hCG; CGB; Human chorionic gonadotropin; Choriogonadotropin subunit beta; Chorionic gonadotropin chain beta; CG-beta |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the core β subunit of the human chorionic gonadotropin hormone (hCG), a hormone produced by a part of the placenta, the syncytiotrophoblast, following implantation. The hormone has an important role during pregnancy, as it interacts with the LHCG receptor in the ovaries to prevent the degeneration of the corpus luteum, and thereby allows the secretion of progesterone during the first trimester. hCG is a heterodimeric glycoprotein, composed of an α and a β domain, of which the α is identical to that of LH and FSH, while the β is unique to hCG. |
| Application Notes: | The binding reactivity of this antibody for human chorionic gonadotropin was determined using ELISA (PMID: 9930677). This antibody is specific for the β-subunit, and can be used in the detection of the hormone in pregnancy tests or in the diagnosis of uterine cancer. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |