Mfg Part Number
Ab04737-10.3
Vector Labs Ab04737-10.3 Anti-H3K27me3 [27F40], Human IgG1, Fc Silent™, lambda (100 μg)
Quick Overview
Vector Labs Ab04737-10.3 Anti-H3K27me3 [27F40], Human IgG1, Fc Silent™, lambda (100 μg)
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 27F40 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Trimethylated Histone H3 Lys27; trimethyl-Histone H3 (Lys27); histone H3; H3K27; Trimethylated histone H3; Histone H3 trimethylated at Lysine 27; nucleosome; H3K27ME3; post translational modification; histone post-translational modification |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is capable of recognizing histone H3 proteins with a trimethylation at Lys27. Methylation is a type of post-translational modification (PTM) which is caused by covalent addition of methyl group to proteins, DNA or other molecules. PTMs have fundamental roles in chromatin structure and function. The PTMs that have taken place in histone proteins can affect gene expression by altering chromatin structure. Histone modifications have also been known as epigenetic markers. Defects in the PTMs pathway have been associated with the occurrence and progression of various human diseases, such as cancer, heart failure, autoimmune diseases, and neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, and Huntington's disease. |
| Application Notes: | This antibody can be used to detect histone H3 proteins trimethylated at lysine 27 (H3K27me3) using ELISA (US10208110). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |