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Mfg Part Number

Ab04739-3.0

Vector Labs Ab04739-3.0 Anti-H4K20me3 [20F109], Mouse IgG2b, lambda (100 μg)

VECTOR LABS

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Vector Labs Ab04739-3.0 Anti-H4K20me3 [20F109], Mouse IgG2b, lambda (100 μg)

$570.70

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Description

Product Class: Purified
Clone ID: 20F109
Synonyms: Trimethylated Histone H4 Lys20; trimethyl-Histone H4 (Lys20); histone H4; H4K20; Trimethylated histone H4; Histone H4 trimethylated at Lysine 20; nucleosome; H4K20ME3; post translational modification; histone post-translational modification
Amount: 100 μg
Application Codes Clone: ELISA
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is capable of recognizing histone H3 proteins with a trimethylation at Lys20. Methylation is a type of post-translational modification (PTM) which is caused by covalent addition of methyl group to proteins, DNA or other molecules. PTMs have fundamental roles in chromatin structure and function. The PTMs that have taken place in histone proteins can affect gene expression by altering chromatin structure. Histone modifications have also been known as epigenetic markers. Defects in the PTMs pathway have been associated with the occurrence and progression of various human diseases, such as cancer, heart failure, autoimmune diseases, and neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, and Huntington's disease.
Application Notes: This antibody can be used to detect histone H4 proteins trimethylated at lysine 20 (H4K20me3) using ELISA (US10208110).

Product Class:	Purified
Clone ID:	20F109
Synonyms:	Trimethylated Histone H4 Lys20; trimethyl-Histone H4 (Lys20); histone H4; H4K20; Trimethylated histone H4; Histone H4 trimethylated at Lysine 20; nucleosome; H4K20ME3; post translational modification; histone post-translational modification
Amount:	100 μg
Application Codes Clone:	ELISA
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is capable of recognizing histone H3 proteins with a trimethylation at Lys20. Methylation is a type of post-translational modification (PTM) which is caused by covalent addition of methyl group to proteins, DNA or other molecules. PTMs have fundamental roles in chromatin structure and function. The PTMs that have taken place in histone proteins can affect gene expression by altering chromatin structure. Histone modifications have also been known as epigenetic markers. Defects in the PTMs pathway have been associated with the occurrence and progression of various human diseases, such as cancer, heart failure, autoimmune diseases, and neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, and Huntington's disease.
Application Notes:	This antibody can be used to detect histone H4 proteins trimethylated at lysine 20 (H4K20me3) using ELISA (US10208110).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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