Mfg Part Number
Ab04780-10.0
Vector Labs Ab04780-10.0 Anti-Autotaxin [ATXB3], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by panning a de novo human Fab-pIX library against biotinylated human ATX beta.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | ATXB3 |
| Synonyms: | ATX; Extracellular lysophospholipase D; LysoPLD; ectonucleotide pyrophosphatases/phosphodiesterases 2; ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; ENPP2; EC:3.1.4.39; EC:3.1.4.4 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted human antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for autotaxin, a secreted lysophospholipase D. In mammals, the enzyme produces phospholipid lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). |
| Application Notes: | The specificity of the original antibody (human Fab) was evaluated via an ELISA, with a binding affinity (KD) of 0.715 nM as measured by SPR. This antibody can be used as part of an antibody pair with Ab04781 [ATXB6] since they exhibit simultaneous binding to ATX (US20150087812A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |