Mfg Part Number
Ab04786-10.0
Vector Labs Ab04786-10.0 Anti-PIVKA-II [PV-Ab1], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with a polypeptide sequence based on the 11th-26th amino acid sequence of PIVKA-II. This region specifically lacked γ-carboxylation, which helped distinguish it from normal thrombin. An additional 8 amino acid sequence was added to enhance immunogenicity. The immunogen was coupled to KLH using EDC as a crosslinker.
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| Product Class: | Purified |
|---|---|
| Clone ID: | PV-Ab1 |
| Synonyms: | Protein induced by vitamin K deficiency-II; protein induced by vitamin K absence-II; abnormal prothrombin glycoprotein |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human PIKVA-II. |
| Application Notes: | The original antibody's specificity was validated via an ELISA. This antibody was successfully used as part of a chemiluminescent detection kit for PIKVA-II, with a detection limit of 1.38 mAU/mL (CN112175925A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |