Mfg Part Number
Ab04792-23.0
Vector Labs Ab04792-23.0 Anti-p-tau [pS396/pS404_1], Rabbit IgG, lambda (100 μg)
Quick Overview
The original antibody was generated by immunizing chickens with phosphorylated tau peptides conjugated to KLH, constructing an scFv phagemid library from spleen and bone marrow RNA, and selecting specific binders through ELISA screening of the phage library against biotinylated phospho-peptides.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | pS396/pS404_1 |
| Synonyms: | ptau; phospho-tau |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; SPR |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 23148212 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Chicken scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for phosporilated human tau protein. |
| Application Notes: | The specificity of the original antibody (chicken scFv, lambda) was evaluated via an ELISA. A chimeric human IgG1 version of the antibody was generated. The chimeric variant preserved the original binding characteristics as demonstrated in an ELISA. The binding affinity (KD) of the chimeric antibody was measured at 2.045 µM via SPR (Shih et al., 2012; PMID: 23148212). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |