Mfg Part Number
Ab04810-1.1
Vector Labs Ab04810-1.1 Anti-CA 19-9 [1116-NS-19-9], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with human colorectal carcinoma cell line SW 1116.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1116-NS-19-9 |
| Synonyms: | CD43; Colorectal carcinoma; CA19-9; sialyl Lewis A; sLe A; 1116-56-2; 1116NS19.9; 1116-NS-19–9 |
| Amount: | 100 μg |
| Application Codes Clone: | RIA; MHA; IF; Crystallization; SPR; FC; IHC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 8372513 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for human colorectal carcinoma cells. |
| Application Notes: | The original version of this antibody was used in a radioimmunoassay (RIA), a mixed Hemadsorption Assay (MHA), and an immunofluorescence (IF) assays to validate its specificity for human colorectal carcinoma cells. It was also tested on fresh tumor tissue from colorectal carcinoma patients, where it was found to bind selectively to tumor cells, but not normal intestinal tissue, further confirming its specificity for colorectal carcinoma (Herlyn et al., 1979; PMID: 286328). This antibody was crystallized with and without its target antigen. Furthermore, in a surface plasmon resonance (SPR) assay a KD of 14.7 µM was measured, and the antigen recognition of an scFv version of this antibody was measured via flow cytometry (FC) (Borenstein-Katz et al., 2021; PMID: 34119488). The use of this antibody in IHC was successfully demonstrated in a doctoral dissertation (Khilji, 2023). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |