Mfg Part Number
Ab04811-2.3
Vector Labs Ab04811-2.3 Anti-Ebola GP [6D8], Mouse IgG2a, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with Venezuelan equine encephalitis (VEE) virus replicons encoding the Ebola glycoprotein from the Mayinga isolate of the Zaire strain of Ebola virus.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 6D8 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Ebola glycoprotein; EboGP; GP1 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; IF; RIPA; WB; Neutralization; In vitro; In vivo |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 22143779 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for the C-terminal portion of Ebola glycoprotein (GP1). |
| Application Notes: | The specificity of the original version of this antibody (mouse IgG2a) was validated via ELISA, IF, RIPA, and WB. In in vitro plaque reduction assays, this antibody achieved 80% plaque reduction at a concentration as low as 6.25 µg/ml. In in vivo experiments with mice and guinea pigs, 6D8 demonstrated protective effects when administered before or shortly after viral exposure (Wilson et al., 2000; PMID: 10698744) (US6875433B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |