Mfg Part Number
Ab04820-2.0
Vector Labs Ab04820-2.0 Anti-Vitamin D binding protein [6A2], Mouse IgG2a, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing New Zealand white rabbits with mouse vitamin D binding protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 6A2 |
| Synonyms: | VDBP; GC; DBP; VDB; Vitamin D-binding protein; Gc-globulin; Group-specific component |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; in vivo; neutralize |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds the mouse vitamin D binding protein (VDBP). This protein is involved in the transport and storage of vitamin D, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. |
| Application Notes: | The binding characterization of this antibody was done using ELISA. This antibody was capable of blocking vitamin D binding protein and helps avoid damage to the synaptic plasticity of neurons by restoring synaptic proteins like PSD95 and Synapsin I in mouse groups treated with this antibody. This antibody was also capable of reducing damage to the dendritic structure of neurons and protect against neuronal damage in mouse groups treated with a combination of VDBP+6A2 (CN118754982). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |