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Mfg Part Number

Ab04822-10.0

Vector Labs Ab04822-10.0 Anti-IL-4 [AbAbS2-IL4], Human IgG1, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing BALB/c mice with human interleukin-4.

$570.70

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Description

Product Class: Purified
Clone ID: AbAbS2-IL4
Synonyms: IL4; BSF-1; Interleukin-4; B-cell stimulatory factor 1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Amount: 100 μg
Application Codes Clone: ELISA; Cytometric bead array
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds human IL-4. Interleukin-4 is a cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. It induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It also induces expression of class II MHC molecules on resting B-cells and enhances both secretion and cell surface expression of IgE and IgG1.
Application Notes: This antibody can be used for detection of IL-4 using ELISA. A combination of AbAbS1-IL4 and AbAbS2-IL4 was used for the detection of IL-4 in a sandwich assay, where AbAbS1-IL4 was used as a coating antibody and AbAbS2-IL4 was used as detection antibody. This combination was also used in the generation of a cytometric bead array (CBA) kit for detection of IL-4. The sensitivity of detection for this antibody pair for the CBA kit was reported to be less than 0.5pg/mL (CN118388645).

Product Class:	Purified
Clone ID:	AbAbS2-IL4
Synonyms:	IL4; BSF-1; Interleukin-4; B-cell stimulatory factor 1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Amount:	100 μg
Application Codes Clone:	ELISA; Cytometric bead array
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody binds human IL-4. Interleukin-4 is a cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. It induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It also induces expression of class II MHC molecules on resting B-cells and enhances both secretion and cell surface expression of IgE and IgG1.
Application Notes:	This antibody can be used for detection of IL-4 using ELISA. A combination of AbAbS1-IL4 and AbAbS2-IL4 was used for the detection of IL-4 in a sandwich assay, where AbAbS1-IL4 was used as a coating antibody and AbAbS2-IL4 was used as detection antibody. This combination was also used in the generation of a cytometric bead array (CBA) kit for detection of IL-4. The sensitivity of detection for this antibody pair for the CBA kit was reported to be less than 0.5pg/mL (CN118388645).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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