Mfg Part Number
Ab04824-1.1
Vector Labs Ab04824-1.1 Anti-IL-6 [5D5H10], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was raised by immunizing mice with the human IL-6 antigen.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 5D5H10 |
| Synonyms: | IL6; IFNB2; BSF-2; CDF; Interleukin-6; IL-6; B-cell stimulatory factor 2; CTL differentiation factor; Hybridoma growth factor; Interferon beta-2; IFN-beta-2 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for human IL-6 and does not bind IL-2, IL-7, IL-15, IL-10, IL-21, GM-CSF and TNF-alpha proteins . Interleukin-6 is a multifunctional cytokine which regulates immune responses, hematopoiesis, tissue regeneration, and inflammatory reactions. Dysregulation of IL-6 is known to be involved in the inflammatory pathways of several autoimmune disorders such as rheumatoid arthritis, Castleman's syndrome, idiopathic juvenile arthritis, neuromyelitis optica spectrum disorder, autoimmune epilepsy and others. |
| Application Notes: | The original mouse IgG antibody binds human IL-6 with a high affinity and has a dissociation constant (Kd) in the nanomolar range. A combination of 5D5D9 and 5D5H10 can be used in a double antibody sandwich ELISA, where 5D5H10 is used as a capture antibody and 5D5D9 is used as a detection antibody. The sensitivity of IL-6 detection for this pair was reported to be 2.344pg/mL (CN118515763). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |