Mfg Part Number
Ab04829-3.3
Vector Labs Ab04829-3.3 Anti-IL-10 [AbAb01-IL10], Mouse IgG2b, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing New Zealand white rabbits with recombinant human IL-10 protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | AbAb01-IL10 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | IL10; IL10A; B-TCGF; TGIF; Interleukin-10; Interleukin 10; Cytokine synthesis inhibitory factor (CSIF) |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human IL-10. Interleukin 10 is a major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. |
| Application Notes: | The original rabbit IgG antibody binds human IL-10 with a high affinity and has a dissociation constant (Kd) of 9.62×10^(-11) M. A combination of AbAb01-IL10 and AbAb02-IL10 can be used in a double antibody sandwich ELISA, where AbAb01-IL10 is used as a capture antibody and AbAb02-IL10 is used as a detection antibody. The sensitivity of human IL-10 detection for this pair was reported to be 125pg/ml (CN114349858). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |