Mfg Part Number
Ab04840-3.0
Vector Labs Ab04840-3.0 Anti-IL-12 [7G11], Mouse IgG2b, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing New Zealand rabbits with recombinant human IL-12 protein containing Ile23-Ser328 sequence of IL-12A and Arg23-Ser219 sequence of IL-12B.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 7G11 |
| Synonyms: | IL12; IL-12p70; IL12p70 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human interleukin 12. It is required for early control of infection and for generation maintenance of acquired protective immunity. |
| Application Notes: | The original rabbit IgG antibody binds human recombinant interleukin-12 protein containing Ile23-Ser328 sequence of IL-12A and Arg23-Ser219 sequence of IL-12B with a binding affinity of Kd=2.14 nM. A combination of 12E3 and 7G11 can be used in a double antibody sandwich ELISA, where 12E3 is used as a capture antibody and biotin-labeled 7G11 is used as a detection antibody. The sensitivity of human IL-12 detection for this pair was reported to be 11.05pg/mL (11.05ng/L) (CN115819580). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |