Mfg Part Number
Ab04842-10.3
Vector Labs Ab04842-10.3 Anti-IL-21 [13A6G6], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with human IL-21 protein.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 13A6G6 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | IL21; Interleukin-21; Za11 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody specifically binds human IL-21, a cytokine with immunoregulatory activity. It promotes the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells. IL-21 has potent anti-tumor activity. It is implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection |
| Application Notes: | This antibody can be used for the detection of human IL-21 using ELISA. A combination of antibodies 3G6D7 and 13A6G6 can be used in a double antibody sandwich ELISA, where 3G6D7 is used as a capture antibody and 13A6G6 is used as a detection antibody (CN117069840B). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |