Mfg Part Number
Ab04861-10.0
Vector Labs Ab04861-10.0 Anti-GD3 [3D2], Human IgG1, lambda (100 μg)
Quick Overview
The original antibody was originated by immunizing mice with multi-antigen peptides GD3P4.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 3D2 |
| Synonyms: | disialogangliosides GD3 |
| Amount: | 100 μg |
| Application Codes Clone: | IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The original antibody is specific for GD3, a tumor-associated antigens. |
| Application Notes: | The original format of the antibody was assessed by immunostaining on a thin-layer chromatography plate (ITLC) using a ganglioside fraction purified from human melanoma tumors. It bound specifically to GD3 and not to any other tested ganglioside. The binding specificity of the original format of the antibody was also investigated using bovine brain ganglioside fraction, where it slightly bound to GT1b. The original format of the antibody bound to the human melanoma SK MEL-28 cells (approximately 14% of the cells were recognized). The original format of the antibody was used for immunostaining of tumor tissue (Popa et al., 2006; PMID: 16458892). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |