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Mfg Part Number

Ab04983-10.3

Vector Labs Ab04983-10.3 Anti-CXCL1 [AbAb10-CXCL1], Human IgG1, Fc Silent™, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing BALB/c mice with recombinant human CXCL1 with a his tag.

$570.70

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Description

Product Class: Purified
Clone ID: AbAb10-CXCL1
Heavy Chain Modification: Fc Silent™
Synonyms: MGSA; NAP-3; GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha (1-73); Melanoma growth stimulatory activity; Neutrophil-activating protein 3
Amount: 100 μg
Application Codes Clone: ELISA
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody specifically recognizes the amino acid sequence 'NGRKACLNPASPIVKKIIEKMLNSDKSN' of human CXCL1. CXCL1 primarily acts as a chemoattractant for several immune cells, especially neutrophils. Upon binding to its receptor CXCR2, CXCL1 activates various signaling pathways, including PI3Kγ/Akt, MAP kinases, and phospholipase-β. CXCL1 is an important molecule in human immune system, playing diverse roles in inflammation, cancer progression, and neurological processes.
Application Notes: This antibody can be used for the detection of human CXCl1 in plasma, urine and other samples. A combination of AbAb01-CXCL1 and AbAb10-CXCL1+AbAb14-CXCL1 can be for the detection of human CXCL1 in a sandwich assay, where AbAb01-CXCL1 was used as a coating antibody and mixture of biotinylated AbAb10-CXCL1 and AbAb14-CXCL1 was used as detection antibody. The sensitivity of detection for this combination was reported to be in the pg/ml range (US9309312B2).

Product Class:	Purified
Clone ID:	AbAb10-CXCL1
Heavy Chain Modification:	Fc Silent™
Synonyms:	MGSA; NAP-3; GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha (1-73); Melanoma growth stimulatory activity; Neutrophil-activating protein 3
Amount:	100 μg
Application Codes Clone:	ELISA
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody specifically recognizes the amino acid sequence 'NGRKACLNPASPIVKKIIEKMLNSDKSN' of human CXCL1. CXCL1 primarily acts as a chemoattractant for several immune cells, especially neutrophils. Upon binding to its receptor CXCR2, CXCL1 activates various signaling pathways, including PI3Kγ/Akt, MAP kinases, and phospholipase-β. CXCL1 is an important molecule in human immune system, playing diverse roles in inflammation, cancer progression, and neurological processes.
Application Notes:	This antibody can be used for the detection of human CXCl1 in plasma, urine and other samples. A combination of AbAb01-CXCL1 and AbAb10-CXCL1+AbAb14-CXCL1 can be for the detection of human CXCL1 in a sandwich assay, where AbAb01-CXCL1 was used as a coating antibody and mixture of biotinylated AbAb10-CXCL1 and AbAb14-CXCL1 was used as detection antibody. The sensitivity of detection for this combination was reported to be in the pg/ml range (US9309312B2).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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