Mfg Part Number
Ab04995-1.1

Vector Labs Ab04995-1.1 Anti-Protective antigen [14B7], Mouse IgG1, kappa (100 μg)

Quick Overview
This antibody was raised by immunizing a female BALB/c mouse with Purified PA, LF, and EF antigens from B. Anthracis.
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Product Class:Purified
Clone ID:14B7
Synonyms:PA; pagA; pag; pXO1-110; BXA0164; GBAA_pXO1_0164; PA-83; PA83; Anthrax toxins translocating protein
Amount:100 μg
Application Codes Clone:ELISA; in vivo; in vitro; neutralization
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:This antibody is specific for the protective antigen of Bacillus anthracis.
Application Notes:The original version of this antibody was used for an ELISA on protective antigen from Anthrax. This antibody was used for an in vivo neutralization assay, the rats were injected with 40 ug of PA, 8 ug of LF, and 4 mg of antibody, it lead to the rat surviving instead of perishing. This antibody was used for an in vitro assay on CHO cells, it showed it was able to neutralize edema toxin with 1 mg of antibody (Little et al., 1988; PMID:3384478). The structure of the original antibody was determined using x-ray crystallography (Leysath et al., 2009; PMID:19361425).
More Information
Brand Vector Labs
UNSPSC 12161500