Mfg Part Number
Ab05022-23.0
Vector Labs Ab05022-23.0 Anti-Clostridium difficile toxin B [CA1153], Rabbit IgG, kappa (100 μg)
Quick Overview
The antibody was generated by immunizing Sprague Dawley rats and half-lop rabbits with various antigens, including synthetic peptides mapping to regions common to both TcdA and TcdB full-length toxins, formaldehyde-inactivated toxoid A, binding domain fragments of Toxin A, binding domain fragments of Toxin B, or combinations of these. Following immunization, B cells were isolated, and the resulting antibodies were subsequently humanized.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | CA1153 |
| Synonyms: | CA164_1153; tcdB; toxB; Toxin B; Glucosyltransferase TcdB |
| Amount: | 100 μg |
| Application Codes Clone: | in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for Toxin B from Clostridium difficile. |
| Application Notes: | The original version of this antibody was used for a neutralization assay, it was tested in combination with CA1125, the best EC50 that was reached was 2.7 ng/ml (Davies et al., 2013; PMID:23324518). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |