Mfg Part Number
Ab05030-10.3
Vector Labs Ab05030-10.3 Anti-DPEP3 [hSC34.28], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
This antibody was raised by immunizing a mouse with A61-S488 from human DPEP3, fused in-frame with a histidine tag.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | hSC34.28 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Dipeptidase 3 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; in vitro; in vivo |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human format, created for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human DPEP3 specifically residues selected from the group consisting of S380, S384, V386, Q248. |
| Application Notes: | This antibody was used for an ELISA on proteins extracted form PDX tumors.This antibody was conjugated to pyrrolobenzodiazepine and used in vitro to test its ability to deliver cytotoxic agents to live tumor cells, during the in vitro test on the OV-S PDX tumor line it was shown that this antibody conjugate could suppress tumor growth. The same antibody conjugate was tested in vivo and showed it was able to suppress tumor growth in immunodeficient mice (US10189910B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |