Mfg Part Number
Ab05047-10.3
Vector Labs Ab05047-10.3 Anti-NMDAR1 [003-102], Human IgG1, Fc Silent™, lambda (100 μg)
Quick Overview
This antibody was raised from human cerebrospinal fluid samples.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 003-102 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | NR1; NMD-R1; hNR1; GluN1; GRIN1; Glutamate receptor ionotropic, NMDA 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1 |
| Amount: | 100 μg |
| Application Codes Clone: | IF; FC; in vitro; ELISA; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human NMDAR1. |
| Application Notes: | This antibody was used for immunofluorescence on NR1-transfected HEK cells. This antibody was used for flow cytometry on Hek cells, it showed positive staining. This antibody was used in vitro on human hippocampal neurons to determine the effect on calcium uptake, it showed a profoundly reduced NMDA-induced calcium influx (Kreye et al., 2016; PMID:27543972). This antibody was used for flow cytometry on NR1–EYFP-transfected HEK293 cells (Ly et al., 2018; PMID:30187160). This antibody was used for immunohistochemistry on mouse brains, it was able to quantify NR1 protein expression (Jurek et al., 2019; PMID:31325344). This antibody was used for an ELISA on the GluN1 subunit bound to a Fc domain and the GluN1-GluN2A subunit bound to a Fc domain, it showed binding to both (Steinke et al., 2023; PMID:36866449). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |