JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Skip to the beginning of the images gallery

Mfg Part Number

Ab05048-12.4

Vector Labs Ab05048-12.4 Anti-NMDAR1 [007-168], Human IgG3, Fc Silent™, kappa (100 μg)

VECTOR LABS

Be the first to review this product

Quick Overview

This antibody was raised from human cerebrospinal fluid samples.

$570.70

Order will ship within 1-3 business days

Description

Product Class: Purified
Clone ID: 007-168
Heavy Chain Modification: Fc Silent™
Synonyms: NR1; NMD-R1; hNR1; GluN1; GRIN1; Glutamate receptor ionotropic, NMDA 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1
Amount: 100 μg
Application Codes Clone: IF; FC; in vitro; ELISA; IHC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG3
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This is a reformatted human IgG3 Fc Silent™ antibody, based on the original human IgG3 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for human NMDAR1, it was shown that a N368Q mutation of NMDAR1 would disrupt binding.
Application Notes: This antibody was used for immunofluorescence on NR1-transfected HEK cells. This antibody was used for flow cytometry on Hek cells, it showed positive staining. This antibody was used in vitro on human hippocampal neurons to determine the effect on calcium uptake, it showed a profoundly reduced NMDA-induced calcium influx (Kreye et al., 2016; PMID:27543972). This antibody was used for an ELISA on the GluN1 subunit bound to a Fc domain and the GluN1-GluN2A subunit bound to a Fc domain, it showed binding to both (Steinke et al., 2023; PMID:36866449). This antibody was used for immunohistochemistry on rat hippocampi, and mouse brains (Wagner et al., 2020; PMID:32735875, Jurek et al., 2019; PMID:31325344). This antibody was used for flow cytometry on NR1–EYFP-transfected HEK293 cells (Ly et al., 2018; PMID:30187160).

Product Class:	Purified
Clone ID:	007-168
Heavy Chain Modification:	Fc Silent™
Synonyms:	NR1; NMD-R1; hNR1; GluN1; GRIN1; Glutamate receptor ionotropic, NMDA 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1
Amount:	100 μg
Application Codes Clone:	IF; FC; in vitro; ELISA; IHC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG3
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This is a reformatted human IgG3 Fc Silent™ antibody, based on the original human IgG3 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for human NMDAR1, it was shown that a N368Q mutation of NMDAR1 would disrupt binding.
Application Notes:	This antibody was used for immunofluorescence on NR1-transfected HEK cells. This antibody was used for flow cytometry on Hek cells, it showed positive staining. This antibody was used in vitro on human hippocampal neurons to determine the effect on calcium uptake, it showed a profoundly reduced NMDA-induced calcium influx (Kreye et al., 2016; PMID:27543972). This antibody was used for an ELISA on the GluN1 subunit bound to a Fc domain and the GluN1-GluN2A subunit bound to a Fc domain, it showed binding to both (Steinke et al., 2023; PMID:36866449). This antibody was used for immunohistochemistry on rat hippocampi, and mouse brains (Wagner et al., 2020; PMID:32735875, Jurek et al., 2019; PMID:31325344). This antibody was used for flow cytometry on NR1–EYFP-transfected HEK293 cells (Ly et al., 2018; PMID:30187160).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

Reviews