Mfg Part Number
Ab05098-10.0
Vector Labs Ab05098-10.0 Anti-uPAR [8D3], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with a combination of three synthetic peptides (AVTYSRSRYLEC, YSRSRYLEC, SRYLEC) derived from the linker region between D1 and D2 of uPAR, conjugated to Keyhole limpet hemocyanin (KLH).
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 8D3 |
| Synonyms: | CD87; U-PAR; MO3; PLAUR; Urokinase plasminogen activator surface receptor; Monocyte activation antigen Mo3 |
| Amount: | 100 μg |
| Application Codes Clone: | inhibit; functional assay; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human urokinase plasminogen activator receptor (uPAR). It plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. Upregulation of uPAR expression at the cell surface, and plasminogen activation, has been linked to a number of conditions including inflammation, wound repair, arthritis, atherosclerosis angiogenesis, tumor invasion and metastasis. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |