Mfg Part Number
Ab05120-23.0
Vector Labs Ab05120-23.0 Anti-Capsular polysaccharide [177.16], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing female BALB/c mice with native, unconjugated group C N. Meningitidis (strain C11) capsular polysaccharide (MCPS).
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| Product Class: | Purified |
|---|---|
| Clone ID: | 177.16 |
| Synonyms: | Capsular PS; meningococcal polysaccharide group C; serogroup C sialic acid containing capsular polysaccharides |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; FELISA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 15589322 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the α(2→9) sialic‑acid backbone of N. meningitidis's serogroup C capsular polysaccharide. |
| Application Notes: | The original antibody format (Mouse IgG1) was generated and evaluated. Its specificity was determined by FELISA. It exhibited a binding pattern of OAc⁻ > MCPS, with 50% binding observed at approximately 0.004 µg/mL and 0.03 µg/mL, respectively, under the assay conditions. This indicates a preference for the de‑O‑acetylated serogroup C capsular polysaccharide. The original antibody's pI was measured to be in the range of 6.8–7.2 (García-Ojeda et al., 2000; PMID: 10603394). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |