Mfg Part Number
Ab05130-10.0

Vector Labs Ab05130-10.0 Anti-Porphyrin [14H7], Human IgG1, lambda (100 μg)

Quick Overview
This antibody was raised by immunizing a BALB/c mouse with Fe(ToCPP)-KLH.
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Product Class:Purified
Clone ID:14H7
Amount:100 μg
Application Codes Clone:ELISA; functional assay
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody is specific for porphyrins, with highest sensitivity for iron porphyrins.
Application Notes:The structure of the Fab fragment of this antibody was determined using x-ray crystallography (Robles et al., 2012; PMID:23240001). This antibody was used for an competitive ELISA on porphyrin, it showed that it bound most strongly to (Ortho-COOMePh)4-porphyrin (De Lauzon et al., 1998; PMID:9799110, Quilez et al., 1996; PMID:8849692). This antibody was used for an peroxidase activity experiment, this antibody showed the ability to catalyse the oxidation of 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) by H202 (Quilez et al., 1996; PMID:8849692).
More Information
Brand Vector Labs
UNSPSC 12161500