Mfg Part Number
Ab05133-13.0
Vector Labs Ab05133-13.0 Anti-Factor VIII [NB2E9], Human IgG4, kappa (100 μg)
Quick Overview
This antibody was raised from PMBCs from a hemophilia A patient with inhibitor LE.
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| Product Class: | Purified |
|---|---|
| Clone ID: | NB2E9 |
| Synonyms: | AHF; Coagulation factor VIII; Antihemophilic factor; Procoagulant component |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; functional assay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG4 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for amino acids E2066 and R2150 of human Factor VIII. |
| Application Notes: | This antibody was used for an ELISA on recombinant human factor VIII, in a further ELISA is was shown that this antibody could inhibit factor VIII binding to vWF, it had a IC50 of 0.25 ug/mL. It was shown that this antibody could inhibit the function of factor VIII up to 85% (Jacquemin et al., 2000; PMID:10607698, Coxon et al., 2021; PMID:33973229). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |