Mfg Part Number
Ab05157-10.0
Vector Labs Ab05157-10.0 Anti-CD206 [antibody 83 ], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing CD206-deficient mice with a mixture of the CD206 antigen and an adjuvant.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | antibody 83 |
| Synonyms: | MMR; Macrophage mannose receptor 1 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; FACS |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for CD206. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The original format of the antibody showed a cytotoxic effect on CD206-positive M2 macrophages in biological tissues. In particular, it showed a significant decrease in CD206-positive M2 macrophages in the visceral fat and subcutaneous fat by FACS analysis. When the original format of the antibody was administrated to mice under a high-fat diet, it showed an improvement in the glucose tolerance disorder and insulin resistance (WO2022244854A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |