Mfg Part Number
Ab05158-23.0
Vector Labs Ab05158-23.0 Anti-CD206 [B11], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing transgenic mice with dendritic cells.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | B11 |
| Synonyms: | MMR; Macrophage mannose receptor 1 |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for CD206. |
| Application Notes: | The original format of the antibody demonstrated reactivity with dendritic cells compared to other cells of hematopoetic lineage (lymphocytes, monocytes, PMNs) and to a less extend to macrophages as assessed by flow cytometry. The original antibody bound in a concentration-dependent manner to dendritic cells. The original format of the antibody bound to dendritic cells from diffienent human tissues (such as lung, bone marrow, heart, pancreas, breast, spleen, kidney) as showed by immunohistochemistry. The scFv an F(ab')2 fragments of the antibody bound to dendritic cells from human tissues flow cytometry. The original format of the antibody imuunoprecipitated dendritic cells expressing CD206. The original format of the antibody could block CD206. The original format of the antibody was efficiently internalized after binding to dendritic cells, as showed by flow cytometry. The original format of the antibody could be used to enhance the processing and presentation of antigens by dendritic cells (US7563876B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |