Mfg Part Number
Ab05159-23.0
Vector Labs Ab05159-23.0 Anti-IGSF1 [WM-A1-3389], Rabbit IgG, lambda (100 μg)
Quick Overview
The original antibody was generated by biopanning a human antibody library against hIGSF1
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | WM-A1-3389 |
| Synonyms: | p120; IgSF1; InhBP; Inhibin-binding protein; Immunoglobulin superfamily member 1; Immunoglobulin-like domain-containing protein 1; Pituitary gland-specific factor 2 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for IGSF1. In particular, the antibody can specifically bind to the C terminus of IGSF1. IGSF1 is a membrane protein encoded by the IGSF1 gene found on the X chromosome of humans and other mammalian species. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The anticancer activity of the original format of the antibody was confirmed in a colon cancer mouse model transplanted with a human colon cancer cell line, where the antibody administration group showed higher tumor growth inhibition efficacy than the negative control group. The anticancer activity of the original format of the antibody was confirmed in mouse colon cancer cell lines MC38 and CT26 implanted mouse model. The antibody administered group showed higher tumor growth inhibition efficacy than the negative control group. The anticancer activity of the original format of the antibody was confirmed in xenograft biliary tract cancer cell line transplantation mouse model. The antibody administration group showed higher tumor growth inhibition efficacy than the negative control group. The orignal format of the antibody showed anticancer activity against head and neck cancer in invitro model (WO2024090916A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |